I found that Canon’s image stabilization generally worked well to extend the shooting range, though as documented in The Sharpest Image, critical sharpness is not found through image stabilization.
The main thing to be aware of is that image stabilization can goof, as this example shows.
I shot this image handheld at 1/200 second at f/7.1 on the EOS 5D Mark II. It looks out of focus, but it isn’t; it’s badly blurred from motion, the motion created by the image stabilization system, since I was holding the camera quite steady. I was not able to repeat this problem, so it’s unclear how common it is.
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